Shilpee Lab Members
Shilpee Dutt, PI
Vipin Kumar, Lab manager
Ganesh Bejjanki, Lab technician
Email ID: teju1090[at]gmail[dot]com, tmahaddalkar[at]actrec[dot]gov[dot]in
I did my B.Sc. Biotechnology from S. S. & L. S. Patkar College of Arts & Science, University of Mumbai and MSc. Biotechnology from University of Mumbai, Santacruz, Mumbai.
The current challenges faced in the area of GBM therapeutics are therapy resistance and recurrence. To understand the molecular mechanisms driving the survival and recurrence of GBM, we have developed an in vitro model of radiation resistance from GBM cell lines and patient samples. Using this model, we have shown that after exposure to a lethal dose of radiation a small percentage of resistant residual cells survive and show multinucleated giant cell phenotype (MNGCs). Importantly, these MNGCs overcome mitotic catastrophe and undergo division to form recurrent population which has newly acquired properties of aggressiveness. My area of interest lies in elucidating the molecular mechanism of MNGC division which will provide insights to target this phenomenon for GBM therapeutics.
Apart from pursuing science, I enjoy making pencil sketches. Although I have not been trained as a singer, I love singing! And last but not the least…I love relishing different cuisines.
Tejashree Mahaddalkar
PhD-SRF
Debashmita Sarkar
PhD-SRF
Email ID: debashmitasarkar710[at]gmail[dot]com
I pursued Integrated M.Sc in Biotechnology (2013-2018) from St. Xavier's College, Kolkata. The main focus of my project is to decipher the role of histone acetyltransferase, GCN5 in DNA Damage Response (DDR) pathway in Glioblastoma.
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Apart from science, I like doodling, listening to music, playing badminton and various android games.
Email ID: abanerjee[at]actrec[dot]gov[dot]in, archis1991[at]gmail[dot]com
I pursued Integrated M.Sc in Life Sciences from Central University of Jharkhand, Ranchi. I am working on the underlying mechanism behind the activation of Histone acetyltransferase-GCN5 in acute myeloid leukemia (AML) using both bioinformatics and functional approach.
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Other than coding and biology, I love being a photography enthusiast and a foodie.
Archisman Banerjee
PhD-SRF (CSIR)
Prachi Singh
PhD-JRF
Email ID: singhprachi3399[at]gmail[dot]com
Hello, I am Prachi Singh, a PhD scholar at the School of Life Sciences, JNU, where I am diving into the fascinating world of Glioblastoma and its recurrence in therapy induced senescent cells. With my Bachelor's and Master's degrees from the University of Delhi, I have built a strong foundation in Cancer biology and therapeutics, which fuels my quest to unravel new ways to tackle this challenging disease.
Outside the lab you'll probably find me curled up with a book on fiction, philosophy or science.
I thrive on deep, meaningful conversations that spark new ideas and perspectives.
And here’s a fun fact: I laugh my way through horror movies, and I firmly believe ice cream is the ultimate fix for just about anything.
Email ID: shiwangichandak[at]gmail[dot]com
I have done my Bachelors and Masters in Biotechnology. Currently, I’m researching the unique role of DUSP6 in DNA damage repair of recurrent GBM.
Outside work, I love painting and watching science documentaries to keep my creativity and curiosity alive.
Shiwangi Chandak
PhD-JRF (CSIR)
Muneeb
JRF (Project)
Email ID: muneebwani[at]gmail[dot]com
I did my BSc with a specialization in Biochemistry and Bioinformatics from S.P. College, Srinagar, and MSc in Clinical Biochemistry from the University of Kashmir. The main focus of my project is to find the interaction of GCN5 with ATM in the DNA damage response pathway in glioblastoma.
Outside the lab, I enjoy playing and watching football, exploring new places through travel, and unwinding over a good cup of coffee or tea.